Novel NAD+ metabolomic technologies and their applications to Nicotinamide Riboside interventions
Nicotinamide adenine dinucleotide (NAD+) is a cofactor in hydride transfer reactions and consumed substrate of several classes of glycohydrolyitc enzymes, including sirtuins. NAD+, its biosynthetic intermediates, breakdown products, and related nucleotides (the NAD metabolome) is altered in many met...
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Format: | Others |
Language: | English |
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University of Iowa
2016
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Online Access: | https://ir.uiowa.edu/etd/3203 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=6533&context=etd |