Fronto-striatal circuitry in children at risk for Huntington's disease

Huntington's disease (HD) is an autosomal dominant neurodegenerative disease caused by a mutation involving an expansion of the CAG trinucleotide repeats in the gene encoding for huntingtin (HTT) protein. The discovery of the disease-causing faulty gene (mutant huntingtin; mHTT) has enabled val...

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Bibliographic Details
Main Author: Lee, Qyong
Other Authors: Nopoulos, Peggy C.
Format: Others
Language:English
Published: University of Iowa 2016
Subjects:
Online Access:https://ir.uiowa.edu/etd/3126
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=6470&context=etd