High-throughput identification and characterization of novel inhibitors of Regulator of G Protein Signaling 17 as pretherapeutic leads for the treatment of lung and prostate cancers

G–Protein Coupled Receptors are one of the most important targets in drug development, making up over 60% of drug targets. Recent studies have implicated a role of Regulator of G–Protein Signaling (RGS) proteins in the development and progression of pa...

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Bibliographic Details
Main Author: Mackie, Duncan Ian
Other Authors: Roman, David L.
Format: Others
Language:English
Published: University of Iowa 2014
Subjects:
Online Access:https://ir.uiowa.edu/etd/1986
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=6324&context=etd