The role of organic cation transporters in the nasal uptake and brain distribution of organic cation substrates
The objective of this study was to investigate the role of organic cation transporters (OCTs) in the uptake of hydrophilic drugs into the olfactory bulb and subsequently to the brain. Two OCT2 substrates, amantadine and cimetidine were used as model drugs for this purpose. Bovine nasal explants (olf...
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| Format: | Others |
| Language: | English |
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University of Iowa
2013
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| Online Access: | https://ir.uiowa.edu/etd/1605 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=5657&context=etd |