The role of the GRB2 family of adaptor proteins in T cell receptor-mediated signaling
CD4+ T cells are critical in the fight against parasitic, bacterial, and viral infections, but are also involved in many autoimmune and pathological disorders. Ligation of the T Cell Receptor (TCR) is the primary signal required for T cell activation proliferation, differentiation and cytokine relea...
Main Author: | Bilal, Mahmood |
---|---|
Other Authors: | Houtman, Jon C. D. |
Format: | Others |
Language: | English |
Published: |
University of Iowa
2015
|
Subjects: | |
Online Access: | https://ir.uiowa.edu/etd/1548 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=5600&context=etd |
Similar Items
-
GRB2 nucleates T cell receptor–mediated LAT clusters that control PLC-γ1 activation and cytokine production
by: Mahmood Yousif Bilal, et al.
Published: (2015-03-01) -
Bridging the Gap: Modulatory Roles of the Grb2-Family Adaptor, Gads, in Cellular and Allergic Immune Responses
by: Deborah Yablonski
Published: (2019-07-01) -
Non-targeting control for MISSION shRNA library silences SNRPD3 leading to cell death or permanent growth arrest
by: Maria Czarnek, et al.
Published: (2021-12-01) -
Optimized models for design of efficient miR30-based shRNAs
by: Olga V Matveeva, et al.
Published: (2012-08-01) -
Aptamer-iRNAs as Therapeutics for Cancer Treatment
by: Mario M. Soldevilla, et al.
Published: (2018-10-01)