The role of the GRB2 family of adaptor proteins in T cell receptor-mediated signaling

CD4+ T cells are critical in the fight against parasitic, bacterial, and viral infections, but are also involved in many autoimmune and pathological disorders. Ligation of the T Cell Receptor (TCR) is the primary signal required for T cell activation proliferation, differentiation and cytokine relea...

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Bibliographic Details
Main Author: Bilal, Mahmood
Other Authors: Houtman, Jon C. D.
Format: Others
Language:English
Published: University of Iowa 2015
Subjects:
Online Access:https://ir.uiowa.edu/etd/1548
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=5600&context=etd