The role of the GRB2 family of adaptor proteins in T cell receptor-mediated signaling
CD4+ T cells are critical in the fight against parasitic, bacterial, and viral infections, but are also involved in many autoimmune and pathological disorders. Ligation of the T Cell Receptor (TCR) is the primary signal required for T cell activation proliferation, differentiation and cytokine relea...
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Format: | Others |
Language: | English |
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University of Iowa
2015
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Online Access: | https://ir.uiowa.edu/etd/1548 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=5600&context=etd |