Regulatory crosstalk and interference between the PCB 126 stimulated AHR and hypoxia stimulated HIF-1α signaling pathways
Polychlorinated biphenyls (PCBs) are synthetic organic chemicals that persist in the environment and are known to be carcinogenic to humans. Virtually all of the deleterious effects of PCB 126, the most potent dioxin-like PCB, are mediated by the aryl hydrocarbon receptor (AhR). By means of the comm...
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| Language: | English |
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University of Iowa
2014
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| Online Access: | https://ir.uiowa.edu/etd/4787 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=5303&context=etd |