A novel iterative reducible ligation strategy for the synthesis of homogeneous gene delivery polypeptides

The ability to safely delivery efficacious amounts of nucleic acids to cells and tissues remains an important goal for the gene therapy field. Viruses are very efficient at delivering DNA, but safety concerns limit their clinical use. Nonviral vectors are not as efficient at DNA delivery, but have a...

Full description

Bibliographic Details
Main Author: Ericson, Mark David
Other Authors: Rice, Kevin G.
Format: Others
Language:English
Published: University of Iowa 2012
Subjects:
Online Access:https://ir.uiowa.edu/etd/3449
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=3450&context=etd