A novel iterative reducible ligation strategy for the synthesis of homogeneous gene delivery polypeptides
The ability to safely delivery efficacious amounts of nucleic acids to cells and tissues remains an important goal for the gene therapy field. Viruses are very efficient at delivering DNA, but safety concerns limit their clinical use. Nonviral vectors are not as efficient at DNA delivery, but have a...
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Format: | Others |
Language: | English |
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University of Iowa
2012
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Online Access: | https://ir.uiowa.edu/etd/3449 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=3450&context=etd |