Cytokine requirements for the differentiation and expansion of Il-17a- and Il-22-producing human Vγ2vδ2 T cells
Human γδ T cells expressing the Vγ2Vδ2 T cell antigen receptor play important roles in immune responses to microbial pathogens by monitoring prenyl pyrophosphate isoprenoid metabolites. Most adult Vγ2Vδ2 cells are memory cytotoxic cells that produce interferon-γ (IFN-γ). Recently, murine γδ T cells...
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Language: | English |
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University of Iowa
2011
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Online Access: | https://ir.uiowa.edu/etd/2751 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=2731&context=etd |