Cytokine requirements for the differentiation and expansion of Il-17a- and Il-22-producing human Vγ2vδ2 T cells

Human γδ T cells expressing the Vγ2Vδ2 T cell antigen receptor play important roles in immune responses to microbial pathogens by monitoring prenyl pyrophosphate isoprenoid metabolites. Most adult Vγ2Vδ2 cells are memory cytotoxic cells that produce interferon-γ (IFN-γ). Recently, murine γδ T cells...

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Bibliographic Details
Main Author: Ness, Kristin Jennifer
Other Authors: Morita, Craig T.
Format: Others
Language:English
Published: University of Iowa 2011
Subjects:
Online Access:https://ir.uiowa.edu/etd/2751
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=2731&context=etd