Toward understanding the role of protein context in the polyglutamine disease, SCA3
The polyglutamine diseases are a clinically heterogeneous group of inherited neurodegenerative disorders caused by expansion of polyglutamine-encoding (CAG)n trinucleotide repeats within the disease genes. It is increasingly clear that the amino acid sequences flanking the polyglutamine expansion in...
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Format: | Others |
Language: | English |
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University of Iowa
2011
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Online Access: | https://ir.uiowa.edu/etd/978 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=2363&context=etd |