Development of PEGylated polyacridine peptides for in vivo gene delivery of plasmid DNA
Gene therapy provides an opportunity to ameliorate several genetic disorders and treat numerous diseases by using nucleic acid-based materials to modulate gene activity. However, the greatest challenge for successful gene therapy applications remains delivery. Two general approaches are currently un...
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Language: | English |
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University of Iowa
2010
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Online Access: | https://ir.uiowa.edu/etd/800 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=1985&context=etd |