The role of the alternative pathway of the complement system in the development of dense deposit disease
Dense Deposit Disease (DDD) causes chronic renal dysfunction which progresses to end-stage renal disease in about half of patients within 10 years of diagnosis. Deficiency of and mutations in complement Factor H (CFH) are associated with the development of DDD, suggesting that dysregulation of the a...
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| Format: | Others |
| Language: | English |
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University of Iowa
2010
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| Online Access: | https://ir.uiowa.edu/etd/635 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=1820&context=etd |