Enzymatic regulation of phosphatidylcholine synthesis via protein ubiquitination

Pulmonary surfactant is a critical surface-active substance consisting of dipalmitoylphosphatidylcholine (DPPtdCho) and key apoproteins that are produced and secreted into the airspace from alveolar type II epithelial cells. Deficiency of the surfactant leads to severe lung atelectasis, ventilatory...

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Bibliographic Details
Main Author: Butler, Phillip Louis
Other Authors: Mallampalli, Rama K.
Format: Others
Language:English
Published: University of Iowa 2010
Subjects:
Online Access:https://ir.uiowa.edu/etd/473
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=1658&context=etd