Enzymatic regulation of phosphatidylcholine synthesis via protein ubiquitination
Pulmonary surfactant is a critical surface-active substance consisting of dipalmitoylphosphatidylcholine (DPPtdCho) and key apoproteins that are produced and secreted into the airspace from alveolar type II epithelial cells. Deficiency of the surfactant leads to severe lung atelectasis, ventilatory...
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Format: | Others |
Language: | English |
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University of Iowa
2010
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Online Access: | https://ir.uiowa.edu/etd/473 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=1658&context=etd |