Cellular lifespan based pharmacodynamic analysis of erythropoiesis

The disposition of cells whose mechanism of death is related to the age of the cell cannot be appropriately represented by pharmacodynamic (PD) models where the elimination rate is related to the number of cells. In cells with age-related death their disposition is determined by their lifespan. Thus...

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Bibliographic Details
Main Author: Freise, Kevin Jay
Other Authors: Veng-Pedersen, Peter
Format: Others
Language:English
Published: University of Iowa 2009
Subjects:
Online Access:https://ir.uiowa.edu/etd/290
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=1475&context=etd