Cellular lifespan based pharmacodynamic analysis of erythropoiesis
The disposition of cells whose mechanism of death is related to the age of the cell cannot be appropriately represented by pharmacodynamic (PD) models where the elimination rate is related to the number of cells. In cells with age-related death their disposition is determined by their lifespan. Thus...
Main Author: | |
---|---|
Other Authors: | |
Format: | Others |
Language: | English |
Published: |
University of Iowa
2009
|
Subjects: | |
Online Access: | https://ir.uiowa.edu/etd/290 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=1475&context=etd |