Syntheses of natural products OSW-1, superstolide A and their derivatives
OSW-1 is a natural saponin and its anticancer activities are 10- to 100-fold more potent than many well-known anticancer agents in clinical use. Its cytotoxicity profile suggests that it may have a unique mode of action that is different from other well-known anticancer agents. However, its mechanis...
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Language: | English |
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University of Iowa
2009
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Online Access: | https://ir.uiowa.edu/etd/255 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=1440&context=etd |