Energetic consequences of structural features and dynamics changes upon nucleotide binding to ribonuclease SA: molecular basis for nucleotide binding specificity
Proteins are often able to distinguish between closely related ligands, thus achieving specificity. A major goal in biophysical chemistry is to understand the molecular basis for protein-ligand recognition. This level of understanding is necessary for developing methods to accurately...
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Language: | English |
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University of Iowa
2004
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Online Access: | https://ir.uiowa.edu/etd/120 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=1305&context=etd |