Energetic consequences of structural features and dynamics changes upon nucleotide binding to ribonuclease SA: molecular basis for nucleotide binding specificity

Proteins are often able to distinguish between closely related ligands, thus achieving specificity. A major goal in biophysical chemistry is to understand the molecular basis for protein-ligand recognition. This level of understanding is necessary for developing methods to accurately...

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Bibliographic Details
Main Author: Schrift, Greta Lynn
Other Authors: Murphy, Kenneth P.
Format: Others
Language:English
Published: University of Iowa 2004
Subjects:
Online Access:https://ir.uiowa.edu/etd/120
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=1305&context=etd