Identification and impact of Topoisomerase II β induced DNA double-strand breaks in Glioblastoma multiforme: NMDA-receptor signaling pathway as target structure

Identification and impact of Topoisomerase II β induced DNA double-strand breaks in Glioblastoma multiforme: NMDA-receptor signaling pathway as target structure

Glioblastoma multiforme (GBM) is a highly lethal and incurable cancer of the central nervous system and current therapies are challenged by GBMs invasive growth and chemo-radioresistance. Ca2+-permeable N-Methyl-D-aspartate receptors (NMDARs) are important for synaptic transmission of excitatory neu...

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Bibliographic Details
Main Author: Lutz, Henrik
Format: Others
Language:en
Published: 2019
Online Access:https://tuprints.ulb.tu-darmstadt.de/8678/7/Dissertation%20Henrik%20Lutz.pdf
Lutz, Henrik <http://tuprints.ulb.tu-darmstadt.de/view/person/Lutz=3AHenrik=3A=3A.html> (2019): Identification and impact of Topoisomerase II β induced DNA double-strand breaks in Glioblastoma multiforme: NMDA-receptor signaling pathway as target structure.Darmstadt, Technische Universität, [Ph.D. Thesis]

Internet

https://tuprints.ulb.tu-darmstadt.de/8678/7/Dissertation%20Henrik%20Lutz.pdf
Lutz, Henrik <http://tuprints.ulb.tu-darmstadt.de/view/person/Lutz=3AHenrik=3A=3A.html> (2019): Identification and impact of Topoisomerase II β induced DNA double-strand breaks in Glioblastoma multiforme: NMDA-receptor signaling pathway as target structure.Darmstadt, Technische Universität, [Ph.D. Thesis]

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