Functional Characterization of Azinomycin Biosynthetic Enzymes
Azinomycins A and B are antitumor compounds isolated from soil bacteria, Streptomyces sahachiroi. The azinomycin structure contains an unusual aziridine [1,2a] pyrrolidine ring and an epoxyvaline moiety which are used in forming DNA cross-links. The biosynthetic gene cluster of azinomycin B has been...
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| Format: | Others |
| Language: | en_US |
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2012
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| Online Access: | http://hdl.handle.net/1969.1/ETD-TAMU-2012-08-11701 |