Structural and Functional Studies of Mycothiol Biosynthesis Precursor Enzyme in Mycobacterium tuberculosis
MshA is a glycosyltransferase that synthesizes the precursor of mycothiol, a low-molecular-weight thiol found exclusively in Actinomycetes, including the virulent pathogen Mycobacterium tuberculosis (Mtb). The structure of MshA from Mtb (herein coined as TbMshA) and its complex with uridine diphosp...
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Format: | Others |
Language: | en_US |
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2012
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Online Access: | http://hdl.handle.net/1969.1/ETD-TAMU-2011-08-9929 |