Suppression of manganese-dependent production of nitric oxide in astrocytes: implications for therapeutic modulation of glial-derived inflammatory mediators

Primary cultured astrocytes were treated with Mn in the absence and presence of proinflammatory cytokines to determine their effect upon stimulation of nitric oxide (NO) production. Treatments of manganese and cytokines raised NO production to intermediate levels, whereas combined treatment raised N...

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Bibliographic Details
Main Author: Wright, Tyler T.
Other Authors: Tjalkens, Ronald B.
Format: Others
Language:en_US
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/1969.1/ETD-TAMU-1045
http://hdl.handle.net/1969.1/ETD-TAMU-1045