Studies of the relationship of protein structure to regulation and catalysis in tyrosine hydroxylase

Tyrosine hydroxylase (TyrH) catalyzes the rate-limiting step in the synthesis of the catecholamine neurotransmitters dopamine, epinephrine, and norepinephrine. Phosphorylation of Ser40 of rat TyrH activates the enzyme by decreasing the affinity for catecholamines. In humans, there are four different...

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Bibliographic Details
Main Author: Sura, Giri Raju
Other Authors: Fitzpatrick, Paul F.
Format: Others
Language:en_US
Published: Texas A&M University 2007
Subjects:
Online Access:http://hdl.handle.net/1969.1/5904