Modeling correlation in binary count data with application to fragile site identification
Available fragile site identification software packages (FSM and FSM3) assume that all chromosomal breaks occur independently. However, under a Mendelian model of inheritance, homozygosity at fragile loci implies pairwise correlation between homologous sites. We construct correlation models for chro...
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| Format: | Others |
| Language: | en_US |
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Texas A&M University
2006
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| Online Access: | http://hdl.handle.net/1969.1/4278 |