Modeling correlation in binary count data with application to fragile site identification

Modeling correlation in binary count data with application to fragile site identification

Available fragile site identification software packages (FSM and FSM3) assume that all chromosomal breaks occur independently. However, under a Mendelian model of inheritance, homozygosity at fragile loci implies pairwise correlation between homologous sites. We construct correlation models for chro...

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Bibliographic Details
Main Author: Hintze, Christopher Jerry
Other Authors: Dahm, P. Fred
Format: Others
Language:en_US
Published: Texas A&M University 2006
Subjects:
Fragile Site
Correlation
Binary Variables
Correlated Bernoulli Trials
Online Access:http://hdl.handle.net/1969.1/4278

Internet

http://hdl.handle.net/1969.1/4278

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