TRANSLATIONAL STUDIES OF TARGETING THE THROMBOXANE A2 RECEPTOR IN CANCER.

TRANSLATIONAL STUDIES OF TARGETING THE THROMBOXANE A2 RECEPTOR IN CANCER.

Thromboxane A2 (TXA2) is an eicosanoid formed by the action of thromboxane A2 synthase (TXS) utilizing the cyclooxygenase product, prostaglandin H2, as the substrate. This prostanoid acts mainly by binding to its cognate thromboxane receptor (TP), a G protein coupled receptor (GPCR). GPCRs convey th...

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Bibliographic Details
Main Author:	Allaj, Viola
Format:	Others
Published:	OpenSIUC 2014
Online Access:	https://opensiuc.lib.siu.edu/theses/1506 https://opensiuc.lib.siu.edu/cgi/viewcontent.cgi?article=2520&context=theses

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