TRANSLATIONAL STUDIES OF TARGETING THE THROMBOXANE A2 RECEPTOR IN CANCER.
Thromboxane A2 (TXA2) is an eicosanoid formed by the action of thromboxane A2 synthase (TXS) utilizing the cyclooxygenase product, prostaglandin H2, as the substrate. This prostanoid acts mainly by binding to its cognate thromboxane receptor (TP), a G protein coupled receptor (GPCR). GPCRs convey th...
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| Format: | Others |
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OpenSIUC
2014
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| Online Access: | https://opensiuc.lib.siu.edu/theses/1506 https://opensiuc.lib.siu.edu/cgi/viewcontent.cgi?article=2520&context=theses |