Energy metabolism and aging
Ames dwarf mice have a spontaneous homozygous Prophet of Pituitary Factor 1 (Prop1) loss-of-function mutation. The Prop1 mutation results in a lack of differentiation of lactotrophs, thyrotrophs, and somatotrophs in the anterior pituitary. Without these endocrine cell types, Ames dwarf mice have ess...
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OpenSIUC
2017
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Online Access: | https://opensiuc.lib.siu.edu/dissertations/1430 https://opensiuc.lib.siu.edu/cgi/viewcontent.cgi?article=2434&context=dissertations |