PHOSPHORYLATION OF NF-ΚB RELA/P65 ON SER536 SIGNALS CANCER CELLS TO DEATH AND ENHANCES CHEMOSENSITIVITY
RelA/p65 is a main subunit of nuclear factor-kappaB (NF-kappaB) that regulates expression of genes involved in cell growth and survival, stress response, and inflammation, but its oncogenic or tumor-suppressive function in tumorigenesis has been highly controversial. Hundreds of NF-kappaB inhibitors...
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| Format: | Others |
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OpenSIUC
2014
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| Online Access: | https://opensiuc.lib.siu.edu/dissertations/801 https://opensiuc.lib.siu.edu/cgi/viewcontent.cgi?article=1804&context=dissertations |