PHOSPHORYLATION OF NF-ΚB RELA/P65 ON SER536 SIGNALS CANCER CELLS TO DEATH AND ENHANCES CHEMOSENSITIVITY

PHOSPHORYLATION OF NF-ΚB RELA/P65 ON SER536 SIGNALS CANCER CELLS TO DEATH AND ENHANCES CHEMOSENSITIVITY

RelA/p65 is a main subunit of nuclear factor-kappaB (NF-kappaB) that regulates expression of genes involved in cell growth and survival, stress response, and inflammation, but its oncogenic or tumor-suppressive function in tumorigenesis has been highly controversial. Hundreds of NF-kappaB inhibitors...

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Bibliographic Details
Main Author: Bu, Yiwen
Format: Others
Published: OpenSIUC 2014
Subjects:
apoptosis
autophagy
chemosensitivity
NF-kappaB
senescence
Online Access:https://opensiuc.lib.siu.edu/dissertations/801
https://opensiuc.lib.siu.edu/cgi/viewcontent.cgi?article=1804&context=dissertations

Internet

https://opensiuc.lib.siu.edu/dissertations/801
https://opensiuc.lib.siu.edu/cgi/viewcontent.cgi?article=1804&context=dissertations

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