THE ROLE OF ATP AND FK-506 BINDING PROTEIN IN THE COUPLED GATING OF SKELETAL RYANODINE RECEPTORS

During skeletal muscle stimulation, there is a summation of local events of Ca2+ release from the sarcoplasmic reticulum, known as Ca2+ sparks. Ca2+ sparks originate from groups of skeletal ryanodine receptors (RyR1) that activate and close in synchrony. This synchrony allows for the rapid and massi...

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Bibliographic Details
Main Author: Neumann, Jacob Trevor
Format: Others
Published: OpenSIUC 2011
Subjects:
ATP
Online Access:https://opensiuc.lib.siu.edu/dissertations/348
https://opensiuc.lib.siu.edu/cgi/viewcontent.cgi?article=1348&context=dissertations