SHORT-CHAIN FATTY ACIDS INDUCED AUTOPHAGY SERVES AS AN ADAPTIVE STRATEGY FOR RETARDING MITOCHONDRIA-MEDIATED APOPTOTIC CELL DEATH

Short-chain fatty acids are the major by-products of bacterial fermentation of undigested dietary fibers in human large intestine. SCFAs, mostly propionate and butyrate, inhibit proliferation and induce apoptosis in colon cancer cells, but clinical trials had mixed results regarding the anti-tumor a...

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Bibliographic Details
Main Author: Tang, Yong
Format: Others
Published: OpenSIUC 2010
Subjects:
Online Access:https://opensiuc.lib.siu.edu/dissertations/159
https://opensiuc.lib.siu.edu/cgi/viewcontent.cgi?article=1159&context=dissertations

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