SHORT-CHAIN FATTY ACIDS INDUCED AUTOPHAGY SERVES AS AN ADAPTIVE STRATEGY FOR RETARDING MITOCHONDRIA-MEDIATED APOPTOTIC CELL DEATH
Short-chain fatty acids are the major by-products of bacterial fermentation of undigested dietary fibers in human large intestine. SCFAs, mostly propionate and butyrate, inhibit proliferation and induce apoptosis in colon cancer cells, but clinical trials had mixed results regarding the anti-tumor a...
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| Format: | Others |
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OpenSIUC
2010
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| Online Access: | https://opensiuc.lib.siu.edu/dissertations/159 https://opensiuc.lib.siu.edu/cgi/viewcontent.cgi?article=1159&context=dissertations |