Modification of the Ca²⁺ Release System of Skeletal Muscle Sarcoplasmic Reticulum Vesicles via Sulfhydryl Oxidation and Tryptic Proteolysis
Isotopic and spectrophotometric assays show that micromolar concentrations of heavy metal ions (particularly Ag⁺ and Hg²⁺) stimulate ATPase activity but inhibit Ca²⁺ uptake in isolated SR vesicles. Both effects are caused by increased Ca²⁺ permeability of the membrane, apparently the result of activ...
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| Format: | Others |
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PDXScholar
1988
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| Online Access: | https://pdxscholar.library.pdx.edu/open_access_etds/1348 https://pdxscholar.library.pdx.edu/cgi/viewcontent.cgi?article=2347&context=open_access_etds |