STUDIES ON THE SIZE AND NON-PLANARITY OF AROMATIC STACKING MOIETY ON CONFORMATION SELECTIVITY AND THERMAL STABILIZATION OF G-QUADRUPLEXES
Targeting DNA has the advantage over proteins for cancer remediation because of the fewer copies of the ligands required for the desired therapeutic effect. Traditionally, covalent DNA binders like alkylating agents have been used to induce genetic instability through the formation of DNA lesions an...
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| Format: | Others |
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Scholarly Commons
2020
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| Online Access: | https://scholarlycommons.pacific.edu/uop_etds/3725 https://scholarlycommons.pacific.edu/cgi/viewcontent.cgi?article=4724&context=uop_etds |