RATIONAL DESIGN OF PEPTIDES BINDING TOWARDS HUMAN PD-L1 USING KNOB-SOCKET MODEL

Programmed death-ligand 1 (PD-L1) is a type 1 transmembrane protein that has been reported to play a vital role in mediating suppressed immunity. The interaction between PD-L1 and PD-1 delivers a negative signal that reduces the proliferation of these T cells and induces apoptosis at the same time....

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Bibliographic Details
Main Author: Zha, Xingchen
Format: Others
Published: Scholarly Commons 2018
Subjects:
Online Access:https://scholarlycommons.pacific.edu/uop_etds/3144
https://scholarlycommons.pacific.edu/cgi/viewcontent.cgi?article=4143&context=uop_etds