Cloning and characterization of the Pichia Pastoris PMR1 gene

Pichia pastoris, a popular protein expression system, is limited in its ability to secrete heterologous proteins. The PMR1 gene, the disruption of which is known to improve the secretion of prochymosin, human prourokinase, and human tissue plasminogen activator in Saccharomyces cerevisiae, was clone...

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Bibliographic Details
Main Author: Grove, Heather Lee
Format: Others
Published: Scholarly Commons 2005
Subjects:
Online Access:https://scholarlycommons.pacific.edu/uop_etds/613
https://scholarlycommons.pacific.edu/cgi/viewcontent.cgi?article=1612&context=uop_etds