Effect of platelet factors and thrombin on multiplication of human bone marrow mesenchymal stem cells cultured in low and high oxygen level in vitro

Background: In the bone marrow, hematopoietic and mesenchymal stem cells form a unique niche, in which oxygen tension is low. Hypoxia may have a role in maintaining stem cell capacity for self-renewal and multipotency. We have shown previously a positive influence of platelet-derived growth factors...

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Bibliographic Details
Main Author: Balghonaim, Abir A.
Published: Scholarly Commons 2012
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Online Access:https://scholarlycommons.pacific.edu/uop_etds/210