Synthesis and conformational study of trans-2-aminocyclohexanol-based pH-triggered molecular switches and their application in gene delivery
Trans-2-Aminocyclohexanol (TACH) is a promising model for pH-triggerable molecular switches with a variety of potential applications. In particular, such a switch, when incorporated into cationic liposomes, provides a novel design of the pH-sensitive helper lipids for gene delivery. Protonation of T...
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| Format: | Others |
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Scholarly Commons
2013
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| Online Access: | https://scholarlycommons.pacific.edu/uop_etds/153 https://scholarlycommons.pacific.edu/cgi/viewcontent.cgi?article=1152&context=uop_etds |