Fliposomes: pH-sensitive liposomes comprising novel trans-2-aminocyclohexanol-based amphiphiles as conformational switches for the liposome mebrane

Fliposomes: pH-sensitive liposomes comprising novel trans-2-aminocyclohexanol-based amphiphiles as conformational switches for the liposome mebrane

As a promising pH-triggerable molecular switch, trans -2-aminocyclohexanol (TACH) has a variety of applications. By introducing two hydrocarbon tails, multiple TACH-based lipids (flipids) have been designed and studied that are able to perform a drastic conformational flip upon protonation, loosenin...

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Bibliographic Details
Main Author: Liu, Xin
Format: Others
Published: Scholarly Commons 2013
Subjects:
Organic chemistry
Pharmacy sciences
Pure sciences
Health and environmental sciences
Amphiphiles
Conformational switching
Controlled release
Fliposomes
Liposomes
Chemicals and Drugs
Chemistry
Medical Pharmacology
Medicinal-Pharmaceutical Chemistry
Medicine and Health Sciences
Pharmaceutical Preparations
Pharmacy and Pharmaceutical Sciences
Physical Sciences and Mathematics
Online Access:https://scholarlycommons.pacific.edu/uop_etds/149
https://scholarlycommons.pacific.edu/cgi/viewcontent.cgi?article=1148&context=uop_etds

Internet

https://scholarlycommons.pacific.edu/uop_etds/149
https://scholarlycommons.pacific.edu/cgi/viewcontent.cgi?article=1148&context=uop_etds

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