BRCA/Fanconi anemia pathway genes in hereditary predisposition to breast cancer
Abstract Two major genes are involved in hereditary predisposition to breast and ovarian cancer – BRCA1 and BRCA2. However, germline mutations in these tumor suppressors account for a maximum 20% of the familial breast cancer cases. A significant portion of the genes predisposing to this disease...
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Format: | Doctoral Thesis |
Language: | English |
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Oulun yliopisto
2011
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Online Access: | http://urn.fi/urn:isbn:9789514294099 http://nbn-resolving.de/urn:isbn:9789514294099 |