Role of altered pH homeostasis and hypoxia in the phenotypic changes of cancer cells
Abstract In mammalian cells the pH gradient between the organelles, cytoplasm and extracellular space is strictly regulated. Maintenance of pH homeostasis is crucial for the normal function of the cell and its organelles. In solid tumours, cells often suffer from hypoxia, deprivation of nutrients a...
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| Format: | Doctoral Thesis |
| Language: | English |
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University of Oulu
2009
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| Online Access: | http://urn.fi/urn:isbn:9789514292767 http://nbn-resolving.de/urn:isbn:9789514292767 |