The role of <em>BACH1</em>, <em>BARD1</em> and <em>TOPBP1</em> genes in familial breast cancer

The role of <em>BACH1</em>, <em>BARD1</em> and <em>TOPBP1</em> genes in familial breast cancer

Abstract Approximately 5–10% of all breast cancer cases are estimated to result from a hereditary predisposition to the disease. Currently no more than 25–30% of these familial cases can be explained by mutations in the known susceptibility genes, BRCA1 and BRCA2 being the major ones. Additional pr...

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Bibliographic Details
Main Author: Karppinen, S.-M. (Sanna-Maria)
Format: Doctoral Thesis
Language:English
Published: University of Oulu 2009
Subjects:
BACH1
BARD1
BRCA1
DNA mutational analysis
TOPBP1
breast neoplasms
genetic predisposition to disease
germ-line mutation
hereditary cancer syndromes
Online Access:http://urn.fi/urn:isbn:9789514291593
http://nbn-resolving.de/urn:isbn:9789514291593

Internet

http://urn.fi/urn:isbn:9789514291593
http://nbn-resolving.de/urn:isbn:9789514291593

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