Human lysyl hydroxylases:characterization of a novel isoenzyme and its gene, determination of the domain structure of the lysyl hydroxylase polypeptides and generation of knock-out mice for the novel isoenzyme
Abstract Lysyl hydroxylase (E.C. 1.14.11.4) catalyzes the formation of hydroxylysine in collagens and other proteins with collagenous domains. The resulting hydroxylysine residues participate in the formation of collagen crosslinks, and serve as attachment sites for carbohydrate units. They have be...
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| Format: | Doctoral Thesis |
| Language: | English |
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University of Oulu
2003
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| Online Access: | http://urn.fi/urn:isbn:951427136X http://nbn-resolving.de/urn:isbn:951427136X |