Regulation of cardiac responses to increased load:role of endothelin-1, angiotensin II and collagen XV
Abstract Chronic overload of the heart is the major cause of left ventricular hypertrophy (LVH) and eventually heart failure. It is generally accepted that autocrine/paracrine factors, such as angiotensin II (Ang II) and endothelin-1 (ET-1) contribute to the development of LVH. Cardiac hypertrophy...
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Format: | Doctoral Thesis |
Language: | English |
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University of Oulu
2002
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Online Access: | http://urn.fi/urn:isbn:9514267214 http://nbn-resolving.de/urn:isbn:9514267214 |