Molekulární biomarkery související s poškozením a opravou DNA: jejich role v procesu karcinogeneze, léčbě a monitorování pacientů
Genome instability represents one of the leading forces driving the onset and development of cancer. It arises as a consequence of the combined effect of DNA damage and errors made by the DNA repair system. In many cancers, DNA damage tolerance and DNA repair pathways are disrupted or deregulated, t...
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Format: | Doctoral Thesis |
Language: | English |
Published: |
2020
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Online Access: | http://www.nusl.cz/ntk/nusl-436324 |