Molekulární biomarkery související s poškozením a opravou DNA: jejich role v procesu karcinogeneze, léčbě a monitorování pacientů

Genome instability represents one of the leading forces driving the onset and development of cancer. It arises as a consequence of the combined effect of DNA damage and errors made by the DNA repair system. In many cancers, DNA damage tolerance and DNA repair pathways are disrupted or deregulated, t...

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Bibliographic Details
Main Author: Vodenková, Soňa
Other Authors: Vodička, Pavel
Format: Doctoral Thesis
Language:English
Published: 2020
Online Access:http://www.nusl.cz/ntk/nusl-436324