Epigenetická regulace HLA genů II. třídy a jejich role u autoimunitních onemocnění
(EN) Type 1 diabetes (T1D) belongs among polygenic multifactorial autoimmune diseases. The highest risk is associated with HLA (human leukocyte antigen) class II genes, including HLA-DQA1 gene. Our aim was to investigate DNA methylation of HLA-DQA1 promoter alleles (QAP) and correlate methylation st...
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| Format: | Doctoral Thesis |
| Language: | Czech |
| Published: |
2017
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| Online Access: | http://www.nusl.cz/ntk/nusl-372347 |