Modulation of human telomerase activity by nucleoside and nucleotide analogues

CONCLUSIONS Considering human telomerase as a promising target of anti-cancer therapy, the thesis deals with the study of inhibitory potency of selected ANP diphosphates towards telomerase, and the capability of nucleoside-type DNA methylation inhibitors to inhibit hTERT expression, knowing that hTE...

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Bibliographic Details
Main Author: Hájek, Miroslav
Other Authors: Votruba, Ivan
Format: Doctoral Thesis
Language:English
Published: 2008
Online Access:http://www.nusl.cz/ntk/nusl-368977