Modulation of human telomerase activity by nucleoside and nucleotide analogues
CONCLUSIONS Considering human telomerase as a promising target of anti-cancer therapy, the thesis deals with the study of inhibitory potency of selected ANP diphosphates towards telomerase, and the capability of nucleoside-type DNA methylation inhibitors to inhibit hTERT expression, knowing that hTE...
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Format: | Doctoral Thesis |
Language: | English |
Published: |
2008
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Online Access: | http://www.nusl.cz/ntk/nusl-368977 |