Příprava nukleosidů, nukleotidů a nukleových kyselin nesoucích ligandy bipyridinového typu
An efficient methodology of construction of base-modified nucleosides bearing oligopyridine ligands, based on the Sonogashira or Suzuki cross-coupling reaction of halogenated nucleosides, was developed. This methodology was then successfully employed in construction of base-modified DNA bearing olig...
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Format: | Doctoral Thesis |
Language: | English |
Published: |
2012
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Online Access: | http://www.nusl.cz/ntk/nusl-326588 |