Panely reportérových linií pro steroidní receptory určené k profilování chemických knihoven a vývoj selektivních ligandů pro estrogenové receptory alfa a beta
of the Ph.D. thesis Steroid hormone receptors represent a major target in the drug discovery. As ligand inducible transcription factors, their activity can be modulated by small lipophilic molecules. The first part of this work describes a preparation of two panels of potent, selective and robust lu...
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Doctoral Thesis |
| Language: | English |
| Published: |
2010
|
| Online Access: | http://www.nusl.cz/ntk/nusl-299196 |