Genetická regulace vývoje končetiny.
Lx in SHR.Lx rat manifests in homozygotes as hindlimb preaxial polydactyly. We showed that a 2,964-bp deletion in Plzf (Promyelocytic leukemia zinc finger) intron 2 is the only candidate for Lx. The deletion removes the most deeply conserved CNE with putative regulatory influence on Plzf expression....
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| Format: | Doctoral Thesis |
| Language: | Czech |
| Published: |
2010
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| Online Access: | http://www.nusl.cz/ntk/nusl-299142 |