Studie o účinku ivermektinu na purinergní P2X4 receptor
The P2X4 receptor is ATP-gated cation channel. It is the only mamrnalian purinergic receptor which is modulated by extracellularly applied ivennectin (IVM). rVM is an allosteric modulator that has several effects on receptor [unction: it increases sensitivity to agonists, potentiates maximum current...
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Format: | Doctoral Thesis |
Language: | Czech |
Published: |
2008
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Online Access: | http://www.nusl.cz/ntk/nusl-290562 |