Studie o účinku ivermektinu na purinergní P2X4 receptor

The P2X4 receptor is ATP-gated cation channel. It is the only mamrnalian purinergic receptor which is modulated by extracellularly applied ivennectin (IVM). rVM is an allosteric modulator that has several effects on receptor [unction: it increases sensitivity to agonists, potentiates maximum current...

Full description

Bibliographic Details
Main Author: Jelínková, Irena
Other Authors: Teisinger, Jan
Format: Doctoral Thesis
Language:Czech
Published: 2008
Online Access:http://www.nusl.cz/ntk/nusl-290562